Renal claudin-14 expression is not required for regulating Mg<sup>2+</sup> balance in mice
نویسندگان
چکیده
Using transgenic models and in vitro assays, this study examined the effect of Mg 2+ on regulating urinary excretion Ca via activation -sensing receptor-claudin 14 (CLDN14) pathway. The suggests that CLDN14 is unlikely to play a significant role compensatory response hypermagnesemia.
منابع مشابه
Claudin-16 and claudin-19 interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium.
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ژورنال
عنوان ژورنال: American Journal of Physiology-renal Physiology
سال: 2021
ISSN: ['1522-1466', '1931-857X']
DOI: https://doi.org/10.1152/ajprenal.00590.2020